Overview
QC Lab Technician Jobs in Needham, MA at Candel Therapeutics
About the Work Unit :
The Karbstein Lab in the Department of Biochemistry at Vanderbilt University is seeking an enthusiastic molecular biology/biochemistry research assistant to aid in the lab’s studies of ribosome assembly, quality control and repair. In addition to providing a better understanding about the cellular mechanisms underlying ribosome integrity, this basic science work is highly relevant to cancer biology, and the biology of aging. The lab relies heavily on biochemistry and molecular biology, as well as yeast genetics. For examples of the type of research that will be undertaken see: Blomqvist et al, 2023, PLoS Genetics; Yang et al, 2023, Mol Cell; and Parker et al, 2024, PLoS Biology.
The lab is a mid-sized lab seeking a research tech who will spend most of their time performing research, with some time spent maintaining lab infrastructure. The new research tech will be directly mentored and instructed by Dr. Karbstein, the Principle Investigator, to learn how to plan, conduct, interpret and present research. The laboratory is a supportive, fast-paced environment for driven candidates who enjoy a collaborative atmosphere. It is expected that the new research tech will produce enough data for a first author publication within 2 years of joining the lab. We have a strong post-baccalaureate training record: our past two research techs each produced enough data for a first author publication and were admitted to top PhD programs in the biomedical sciences. The lab strives to be a diverse, inclusive, and equitable working environment; prioritizes personal growth and wellness; and is committed to work-life balance. Overall, this is an excellent opportunity for any recent college graduate looking to obtain research experience before applying to graduate school or medical school.
Key Functions and Expected Performances:
Assists in Research and Development:
Uses protein gels and Western blotting to analyze ribosome assembly factors and ribosomal proteins
Uses Northern blotting to analyze ribosome assembly in cells
Uses agarose gels to analyze PCR screens and PCR reactions
Generates yeast strains
Uses quantitative growth measurements to monitor genetic interactions
Designs and clones proteins and RNAs for yeast in vivo work and in vitro assays
Expresses and purifies proteins in bacteria
Performs general lab and administrative duties:
Prepare buffers and reagents.
Order supplies
Receive packages
Other tasks as directed by supervisor
Supervisory Relationships :
Might supervise interns, work-study students or undergraduate researchers.
The position reports administratively and functionally to the PI.
Education and Certifications:
A Bachelor’s degree in cellular biology, molecular biology, biochemistry, or a related field from an accredited institution of higher education is necessary .
Experience and Skills :
Ability to perform all basic calculations related to buffer composition (Molarity, dilution factor, etc.) is necessary .
Being comfortable in learning new assays is necessary .
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Title: QC Lab Technician
Company: Candel Therapeutics
Location: Needham, MA
